Human mesenchymal stem cell secretome increases hepatocyte growth factor expression and promotes liver regeneration in Wistar rats with cholestasis

Globally, the annual mortality rate due to liver cirrhosis is 2.2%, which ranks 12th as the cause of death in the United States.Human mesenchymal stem cell secretome (Hu-MSC-S) is known to reduce liver injury and inflammation.Thus, the present study aims to determine the effect of Hu-MSC-S on hepatocyte growth factor (HGF) expression and liver rege

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